Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website https://jnr.elmerpub.com

Original Article

Volume 16, Number 1, March 2026, pages 22-29


Utilization of Stroke Kit Antihypertensives Prior to Thrombolysis in Acute Ischemic Stroke: A Single-Center Retrospective Audit

Figure

↓  Figure 1. Flow chart representing included participants.
Figure 1.

Tables

↓  Table 1. Patient Demographics (n = 6)
 
BPH: benign prostate hyperplasia; HTN: hypertension; MGUS: monoclonal gammopathy of undetermined significance; TIA: transient ischemic attack.
Age (years)
  Mean 63.2
  Range 29–85
  Standard deviation 19.76
Gender
  Male 5 (83.3%)
  Female 1 (16.7%)
Past medical history
  Left Lobectomy 1 (16.7%)
  Lung nodules 1 (16.7%)
  BPH 1 (16.7%)
  MGUS 1 (16.7%)
  Previous stroke 1 (16.7%)
  Hypercholesteremia 1 (16.7%)
  Meningioma 1 (16.7%)
  TIA 1 (16.7%)
  HTN 2 (33.3%)
  Renal impairment 1 (16.7%)
  Systemic lupus erythematosus 1 (16.7%)
  Gastric cancer 1 (16.7%)
Nil medical conditions 2 (33.3%)

 

↓  Table 2. Hydralazine Blood Pressure Lowering Effect and NIHSS Score
 
BP: blood pressure; DBP: diastolic blood pressure; SBP: systolic blood pressure.
Median baseline BP (mm Hg) (n = 6)
  SBP 183.5
  Range 180–208
  DBP 101.0
  Range 79–131
Median BP after first dose of hydralazine (mm Hg) (n = 6)
  SBP 164.5
  Range 135–178
  DBP 90
  Range 77–109
Median lowest BP after administration of hydralazine (mm Hg) (n = 6)
  SBP 148
  Range 117–166
  DBP 88.5
  Range 77–114
Time to target BP (min) (n = 6)
  Median 4.5
  Range 2–18
  Standard deviation 6.31
Total hydralazine dose administrated (mg) (n = 6)
  Median 4.58
  Range 2.5–7.5
  Standard deviation 1.02
Baseline NIHSS score (n = 4)
  Median 7.75
  Range 2–15
  Standard deviation 5.62
NIHSS score post thrombolysis (n = 4)
  Median 3.25
  Range 0–8
  Standard deviation 3.40

 

↓  Table 3. Hydralazine Administration Time and Door to Needle Time
 
Time hydralazine was administrated Location of hydralazine obtained Time taken to receive hydralazine from initial ED presentation (min) Door-to-needle time (min)
ED: emergency department; RMR: resuscitation medication room; SK: stroke kit.
8:03 pm SK 29 46
12:04 pm RMR 63 79
5:55 pm RMR 84 99
1:52 am RMR 119 139