Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website https://jnr.elmerpub.com

Original Article

Volume 16, Number 1, March 2026, pages 22-29


Utilization of Stroke Kit Antihypertensives Prior to Thrombolysis in Acute Ischemic Stroke: A Single-Center Retrospective Audit

Figure

↓  Figure 1. Flow chart representing included participants.
Figure 1.

Tables

↓  Table 1. Patient Demographics (n = 6)
 
BPH: benign prostate hyperplasia; HTN: hypertension; MGUS: monoclonal gammopathy of undetermined significance; TIA: transient ischemic attack.
Age (years)
  Mean63.2
  Range29–85
  Standard deviation19.76
Gender
  Male5 (83.3%)
  Female1 (16.7%)
Past medical history
  Left Lobectomy1 (16.7%)
  Lung nodules1 (16.7%)
  BPH1 (16.7%)
  MGUS1 (16.7%)
  Previous stroke1 (16.7%)
  Hypercholesteremia1 (16.7%)
  Meningioma1 (16.7%)
  TIA1 (16.7%)
  HTN2 (33.3%)
  Renal impairment1 (16.7%)
  Systemic lupus erythematosus1 (16.7%)
  Gastric cancer1 (16.7%)
Nil medical conditions2 (33.3%)

 

↓  Table 2. Hydralazine Blood Pressure Lowering Effect and NIHSS Score
 
BP: blood pressure; DBP: diastolic blood pressure; SBP: systolic blood pressure.
Median baseline BP (mm Hg) (n = 6)
  SBP183.5
  Range180–208
  DBP101.0
  Range79–131
Median BP after first dose of hydralazine (mm Hg) (n = 6)
  SBP164.5
  Range135–178
  DBP90
  Range77–109
Median lowest BP after administration of hydralazine (mm Hg) (n = 6)
  SBP148
  Range117–166
  DBP88.5
  Range77–114
Time to target BP (min) (n = 6)
  Median4.5
  Range2–18
  Standard deviation6.31
Total hydralazine dose administrated (mg) (n = 6)
  Median4.58
  Range2.5–7.5
  Standard deviation1.02
Baseline NIHSS score (n = 4)
  Median7.75
  Range2–15
  Standard deviation5.62
NIHSS score post thrombolysis (n = 4)
  Median3.25
  Range0–8
  Standard deviation3.40

 

↓  Table 3. Hydralazine Administration Time and Door to Needle Time
 
Time hydralazine was administratedLocation of hydralazine obtainedTime taken to receive hydralazine from initial ED presentation (min)Door-to-needle time (min)
ED: emergency department; RMR: resuscitation medication room; SK: stroke kit.
8:03 pmSK2946
12:04 pmRMR6379
5:55 pmRMR8499
1:52 amRMR119139