Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website https://jnr.elmerpub.com

Original Article

Volume 15, Number 1, January 2025, pages 33-38


The Role of Erythrocyte Sedimentation Rate as a Prognostic Factor in Intracerebral Hemorrhage

Figure

Figure 1.
Figure 1. Mortality and functional impairment by hemorrhage type.

Tables

Table 1. Patient Demographics and Clinical Characteristics
 
CharacteristicTotal (n = 82)High ESR (n = 35)Normal ESR (n = 47)
ESR: erythrocyte sedimentation rate; GCS: Glasgow Coma Scale; ICH: intracerebral hemorrhage.
Age (years)65 (47 - 89)68 (47 - 89)62 (47 - 89)
Male (%)54.957.153.2
Female (%)45.142.946.8
GCS (score)10.59.811.2
ICH volume (mL)42.646.835.2
Hypertension (%)72.577.168.1
Diabetes (%)2528.621.3
Atrial fibrillation (%)18.722.914.9

 

Table 2. Secondary Outcomes and Functional Impairment at 6 Months
 
OutcomeTotal (n = 82)High ESR (n = 35)Normal ESR (n = 47)PSensitivitySpecificityPPV (%)NPV (%)
ESR: erythrocyte sedimentation rate; PPV: positive predictive value; NPV: negative predictive value.
Mortality (%)13.420.08.50.0363.2%61.8%20%91.5%
Functional impairment (%)56.165.734.00.00265.2%70.8%85.7%53.2%
Mean hospital stay (days)18.512.30.01
Rehabilitation needs (%)58.631.90.005

 

Table 3. Logistic Regression Analysis
 
VariableOR95% CIP value
ESR: erythrocyte sedimentation rate; OR: odds ratio; CI: confidence interval; ICH: intracerebral hemorrhage.
Elevated ESR (mortality)2.51.2 - 5.30.01
Elevated ESR (functional impairment)3.11.5 - 6.50.002
Age (years)1.051.02 - 1.08< 0.001
ICH volume (mL)1.031.01 - 1.050.01

 

Table 4. Correlation with Inflammatory Markers
 
MarkerCorrelation (r)P value
CRP: C-reactive protein.
CRP0.65< 0.001
Leukocyte count0.530.01

 

Table 5. Subgroup Analysis
 
SubgroupOR95% CIP value
OR: odds ratio; CI: confidence interval.
Age > 70 (mortality)3.81.7 - 8.30.001
Gender (male, functional impairment)3.41.7 - 7.00.001