Journal of Neurology Research, ISSN 1923-2845 print, 1923-2853 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Neurol Res and Elmer Press Inc
Journal website https://jnr.elmerpub.com

Original Article

Volume 15, Number 2, March 2025, pages 71-76

The Impact of Metabolic Control on Limb Differences in Peripheral Neuropathy: A Pilot Study

Figures

↓  Figure 1. Differences in electrochemical skin conductance (ESC) differences between limbs (n = 34). Analysis of variance. Data are presented as mean ± standard error of mean (SEM). *Statistically significant from left hand (LH), left foot (LF), and right foot (RF). †Statistically significant from LF and RF.
Figure 1.
↓  Figure 2. Relationships between fasting glucose and electrochemical skin conductance (ESC) in (a) left hand (LH), (b) right hand (RH), and (c) right foot (RF) (n = 34). Pearson’s correlation.
Figure 2.

Table

↓  Table 1. Overall Participant Characteristics
 
Variable Overall (n = 34) Men (n = 8) Women (n = 26) P-value
Data are presented as mean ± SD; independent samples t-test. *Statistically significant. BMI: body mass index; BUN: blood urea nitrogen; HbA1c: hemoglobin A1c; NHB: non-Hispanic Black; NHW: non-Hispanic White.
Demographic
  Age (years) 57 ± 14 57 ± 11 57 ± 15 0.954
  Race (NHW/NHB) 24/10 6/2 18/8 0.763
  Height (cm) 65.6 ± 4.0 69.8 ± 4.2 64.3 ± 3.0 < 0.001*
  Weight (kg) 184 ± 31 205 ± 25 178 ± 30 0.021*
  BMI (kg/m2) 30.1 ± 5.2 29.6 ± 2.5 30.3 ± 5.8 0.752
Clinical laboratory values
  Glucose (mg/dL) 107 ± 34 109 ± 27 106 ± 36 0.841
  HbA1c (%) 5.9 ± 1.1 6.0 ± 0.5 5.9 ± 1.2 0.853
  BUN (mg/dL) 15.3 ± 5.7 16.1 ± 5.1 15.0 ± 6.0 0.646
  Vitamin B12 (pg/mL) 1,086 ± 600 717 ± 158 1,173 ± 635 0.178
  Folate (ng/mL) 16.9 ± 5.3 13.7 ± 4.8 17.6 ± 5.3 0.189
  Vitamin D (ng/mL) 46.2 ± 32.4 40.5 ± 14.4 47.6 ± 35.8 0.705