Papillary Fibroelastoma Causing Large-Vessel Ischemic Stroke in a Young Patient: Histopathologically Confirmed Tumor Embolism Treated With Mechanical Thrombectomy

Authors

  • Ian Kim
  • Thomas R. Marotta
  • David G. Munoz

DOI:

https://doi.org/10.14740/jnr1117

Keywords:

Papillary fibroelastoma, Ischemic stroke, Tumor embolism, Mechanical thrombectomy, Large-vessel occlusion

Abstract

Papillary fibroelastoma (PFE) is a benign cardiac tumor that, despite having significant embolic potential, is typically an uncommon cause of large-vessel ischemic stroke. We report a 19-year-old female who presented with acute aphasia and right hemiplegia due to a left middle cerebral artery M1 occlusion and was successfully treated with mechanical thrombectomy. Histopathologic examination of the retrieved embolus established the diagnosis. This case underscores the diagnostic importance of pathological examination of thrombectomy specimens when identifying rare cardioembolic etiologies of cryptogenic stroke.

Author Biographies

  • Thomas R. Marotta, Department of Medical Imaging – Neuroradiology, University of Toronto, Toronto, Ontario, Canada

    Professor, Department of Medical Imaging (Neuroradiology), University of Toronto, Toronto, Canada.

  • David G. Munoz, Department of Laboratory Medicine & Pathobiology – Neuropathology, University of Toronto, Toronto, Ontario, Canada

    Professor, Department of Laboratory Medicine & Pathobiology (Neuropathology), University of Toronto, Toronto, Canada.

Downloads

Published

2026-08-04

Issue

Section

Case Report

How to Cite

1.
Kim I, Marotta TR, Munoz DG. Papillary Fibroelastoma Causing Large-Vessel Ischemic Stroke in a Young Patient: Histopathologically Confirmed Tumor Embolism Treated With Mechanical Thrombectomy. J Neurol Res. 2026;16(3):180-185. doi:10.14740/jnr1117

Similar Articles

11-20 of 48

You may also start an advanced similarity search for this article.